Semantic Interoperability and HL7

In 2013, the board of directors of the Healthcare Information and Management Systems defined the term interoperability as: the ability of health information systems to work together within and across organizational boundaries in order to advance the effective delivery of healthcare for individuals and communities. Summarize the major challenges associated with interoperability and highlight the possible solutions
Note: This is a discurssion so i need not more than half a page.
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